Protein Unfolding Pathways

About the project:

The project is focused on the development of a novel way to approach protein folding pathways by considering a systematic geometric approach to unfolding a protein, and then folding it back up again using molecular dynamics principles, with the unfolding pathway as a "guide". This approach is inspired by the way in which origami is done, and is a novel approach to protein folding. The project is supervised by Prof. Hugh Patterton, Director of the Centre for Bioinformatics and Computational Biology at Stellenbosch University.

Technology used:

Python, BioPython, SciPy